• Treatment of skin aging and photoaging
• Enhances the elasticity and firmness of the skin
• Retinol concentrate with direct action on the collagen fibers
• Suitable for mature skin accustomed to retinol
• 0.5% Retinol encapsulated in liposomes
• With antioxidant and depigmenting glycyrrhetinic acid
• Also contains niacinamide and hyaluronic acid
• With maximum tolerance and stability

Sesderma Retises Nano 0.50% Gel With Retinol & Hyaluronic Acid For Photoaging & Wrinkles is a fluid texture gel with 0.50% high tolerance pure liposomal Retinol which has intensive anti-aging effect that improves texture, reduces the depth of wrinkles and evens out skin tone to eliminate residual spots and marks. Retinol being encapsulated in liposomes considerably improves the tolerance of the active ingredient. It superficially exfoliates to remove excess dead cells and melanin deposits. Retinol is the only active ingredient that acts on collagen at 3 levels: repairs (the damage over time has led to the fibers) + stimulation (of new collagen fibers) + protection (to inhibit collagenase). It also regulates melanocyte activity altered by reducing blotchy skin and stimulates proliferation of epidermal keratinocytes (exfoliating). Nicotinamide reduces the transfer of melanosomes to keratinocytes (depigmenting), stimulates the production of new collagen, protects the skin from free radical activity, it regulates the synthesis of ceramides (hydrating) and prevents inflammation of the skin.

• Acts on collagen fibers at 3 levels: Repair, stimulation and protection
• Reduces spots and improves skin texture
• Promotes the natural moisturizing of the skin from the innermost layers
• Comes with ingredients having antibacterial and anti-inflammatory effects
• Liposomal Retinol makes the gel much more tolerable
• Reduces the depth of wrinkles and expression lines
• Unifies the skin tone and corrects the pigmentation
• Reduces stains and residual scars

• Apply to your previously clean and dry face at night on alternate days for 2-3 months and after this period apply every night.
• IMPORTANT: Due to its Retinol content, it can cause a slight itching, if it does not stop, apply every other day until it is tolerated and can be used daily.
• Currently, there’s no clear understanding of how much retinol is safe during pregnancy. For this reason, it’s recommended that pregnant and nursing mothers avoid the use of this product.
• Note that it is better to use retinoids only during your night routine, in the case of periods of frequent sun exposure.